If Kudo is bound to a dedicated widget in a given page, you can run commands directly using the editor's JS API.
Run command whitelisted in Default Files\OEM Commands\commands.xml:
window.getXeDocument().RunCheckedCmd(commandString);
Where the commandString is your command you’d like to run including parameters you want to pass.
Either
"_YourCommand Param1 Param2"
or
"_YourCommand\nParam1\nParam2"
RunCheckedCmd returns a promise. If you are interested in the result, call it like
window.getXeDocument().RunCheckedCmd(commandString).then(function (result) {});